What is Alzheimer’s Disease?

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What is Alzheimers Disease

Alzheimer’s disease is a brain disorder that causes memory loss and other problems with thinking, learning and behavior. It is the most common form of dementia.

The disease is caused by abnormal deposits called plaques and tangles in the brain. Plaques are made of beta-amyloid protein fragments, while tangles are bundles of tau protein inside nerve cells. Both interfere with brain function and cause cell death.

That cause alzheimer

Alzheimer’s disease is caused by a combination of genetic, environmental and lifestyle factors that change how your brain works. It’s a progressive, incurable disease that causes memory loss and other symptoms.

Basically, the disease occurs when the proteins that make up brain cells, known as neurons, fail to function normally. This can trigger a series of events that eventually lead to cell death.

Scientists aren’t completely sure how this happens, but they believe that Alzheimer’s disease is caused by abnormal buildup of two proteins. These are beta-amyloid and tau. These proteins clump together, and form deposits called plaques and tangles in the brain.

When these protein clumps form, they can block the brain’s ability to communicate with other cells and cause damage. Over time, these deposits can grow large and spread throughout the brain, causing irreversible changes in memory and thinking skills.

Researchers think that this damage starts in the brain’s memory center and then slowly spreads to other parts of the brain. Symptoms develop over months or years and often start in the middle age.

Some people may not have any symptoms at all, but this isn’t normal. It’s important to get your doctor’s attention if you are having problems remembering or remembering things that aren’t familiar.

If someone’s memory worsens and they have difficulty with their day-to-day activities, this is a sign that they could be developing Alzheimer’s disease. They might begin to get lost, have trouble with communication and need help with basic activities like dressing or using the toilet.

Other signs of Alzheimer’s disease include difficulty finding words, a lack of coordination and poor vision or spatial awareness. This can be particularly noticeable if a person is losing their balance or spilling something on themselves or if they can’t find things easily.

These symptoms are typically mild in the early stages and can be treated with medication. These medications can help stabilise or slow the decline in memory and thinking for a while. They may also be used to treat depression, anxiety or sleep problems.

The most effective way to prevent Alzheimer’s is by making healthy choices and taking steps to improve your overall health. You can lower your risk by avoiding tobacco, drinking plenty of water, eating well and getting regular exercise.

Signs of alzheimer’s disease

Alzheimer’s Disease is a serious condition that affects memory and thinking skills. It can happen suddenly or gradually, depending on the stage of the disease. It usually starts in older people, and it’s more common in women than men.

The first symptoms of Alzheimer’s tend to be forgetfulness or confusion. This is because it affects the parts of the brain that are important for remembering. It can also be difficult to get around and remember where you left things.

You may not be able to carry out everyday tasks like driving or doing laundry without help. This can become more difficult as the disease progresses and you need more assistance with your daily life.

Often, you’ll forget someone’s name or phone number only to realise it later. It’s normal to occasionally forget something, but if this happens more often, it could be a sign that you have Alzheimer’s.

Some people with Alzheimer’s develop a build-up of protein deposits called plaques and tangles in and around nerve cells. These proteins disrupt the way nerve cells work.

Plaques and tangles can form in many areas of the brain, but they are most likely to start in the part of the brain that is involved with memory. They can also form in the area of the brain that processes language, and they may spread to other areas of the brain as the disease progresses.

These deposits are made up of a protein fragment called beta-amyloid and twisted fibers of another protein called tau. Scientists don’t know exactly what causes these to form, but they are thought to play a crucial role in blocking the communication that nerve cells need to function properly.

A person with Alzheimer’s will also lose the ability to think clearly, to remember new information and to make decisions. They may also have trouble communicating with others and responding to emotions.

The signs of Alzheimer’s vary from person to person and can be hard to spot. It’s important to talk to your doctor about them. They can then do a few tests to confirm the diagnosis and rule out other conditions that might be causing your symptoms.

Treatment for alzheimer’s disease

There’s no cure for Alzheimer’s disease, but there are medications that can slow or ease symptoms. These medicines help improve a person’s memory and thinking, decrease stress and promote quality of life for those with the disease and their caregivers.

Doctors typically start a patient on a low dose of a medication, and increase the amount gradually over time. This process is called “medication adjustment” and can take anywhere from several months to several years.

Medications for Alzheimer’s include acetylcholine (ACh) and other chemicals that help the brain function normally. These drugs are called cholinesterase inhibitors. They work by increasing the amount of acetylcholine in the brain, which helps nerve cells communicate with each other and carry out tasks such as memory, thought and judgment.

These drugs are usually taken by mouth as a pill or a liquid. Some people also use skin patches that deliver a cholinesterase inhibitor in a gel form.

Other medications used for mild to moderate Alzheimer’s are donepezil (Aricept), galantamine (Razadyne) and rivastigmine (Exelon). These drugs increase the amount of acetylcholine that’s available in the brain. They are taken by mouth and can cause some side effects, such as nausea, vomiting or diarrhea.

Memantine (Namenda) is another medication that’s approved for treating people with moderate-to-severe Alzheimer’s. It is taken by mouth or in a syrup. It reduces the amount of glutamate, a chemical messenger that’s involved in brain functions such as learning and memory.

A new drug called Aduhelm, which is infused intravenously, was recently approved to treat some people with mild Alzheimer’s-related dementia. But it has mixed effectiveness data and is expensive.

Researchers are working to develop more effective treatments for the disease. This will require new ways of diagnosing and monitoring the disease, identifying patients for clinical trials, and recruiting people to participate in these studies.

If you have dementia, ask your doctor if you are eligible for a clinical trial. This is a great way to participate in vital Alzheimer’s research and improve the lives of people living with dementia. The Alzheimer’s Association offers TrialMatch(r), a free clinical studies matching service, to help you find an appropriate study for you or your loved one.

How to prevent alzheimer’s disease

Alzheimer’s disease is a serious condition that affects memory and thinking. The disease isn’t a normal part of aging, but you can take steps to help prevent it from developing.

The most common risk factor is getting older, but you can also lower your risk by making lifestyle changes. For example, eat a healthy diet and get regular exercise. Avoid smoking and alcohol use, and keep your cholesterol and blood pressure under control.

Keeping your brain active through lifelong learning can also help. This type of activity is called cognitive stimulation, which can help slow the development of Alzheimer’s.

Genetics may also play a role in your risk of developing Alzheimer’s. Research suggests that certain gene changes increase your risk of the disease.

Another risk factor is having a family history of the condition. If you have a close relative with the disease, your risk is about double that of someone without a family history.

There are other factors that may raise your risk, such as head trauma or mild memory problems. However, these risk factors are not always linked to Alzheimer’s disease.

It is not clear what causes Alzheimer’s, but scientists think it is caused by a combination of changes in the brain and damage to blood vessels that supply the brain.

A new study found that several of the same things that improve heart and blood vessel health can also lower your risk of Alzheimer’s. These include a healthy diet, physical exercise, adequate sleep, and not smoking.

Taking a high-quality multivitamin can also help your brain. For example, the antioxidants in vitamin E can protect the brain from the tangles that develop in Alzheimer’s.

You can take a daily supplement of 15 milligrams of vitamin E from seeds, nuts, leafy green vegetables and whole grains. This vitamin is a good way to increase your levels of the antioxidants that protect your brain from tangles, said Dr. Barnard, a Harvard Medical School researcher.

Increasing your intake of omega-3 fatty acids from fatty fish such as salmon, mackerel and sardines may also reduce your risk of Alzheimer’s. In addition, taking a vitamin B12 supplement can also decrease your risk of the disease.

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